Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 3/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24672308 | 1.00 | NT5E (0.40) | NT5ESLC29A1ADORA2AADORA2B | |
| SCHEMBL24672301 | 0.81 | SMN1; SMN2 (0.50) | NT5EADORA2AADORA2B | |
| SCHEMBL27195225 | 0.81 | SMN1; SMN2 (0.50) | NT5EADORA2AADORA2B | |
| SCHEMBL27206777 | 0.81 | SMN1; SMN2 (0.50) | NT5EADORA2AADORA2B | |
| SCHEMBL30008245 | 0.81 | SMN1; SMN2 (0.50) | NT5EADORA2AADORA2B | |
| SCHEMBL27195138 | 0.73 | NT5E (0.38) | NT5EADORA2AADORA2B | |
| SCHEMBL30008289 | 0.73 | NT5E (0.38) | NT5EADORA2AADORA2B | |
| SCHEMBL24672706 | 0.72 | NT5E (0.47) | NT5E | |
| SCHEMBL9851714 | 0.71 | ALDH1A1 (0.43) | NT5ESLC29A1 | |
| SCHEMBL26672135 | 0.69 | NT5E (0.51) | NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237747-A1 | SMALL MOLECULAR CD73 ANTAGONIST AND USE THEREOF | 四川海思科制药有限公司 | 2022-11-17 | — | — | WO | disclosed |