SCHEMBL24672691

SCHEMBL24672691

C[C@H](O)CN1CCN(CC(O)c2ccccc2)CCN(C[C@H](C)O)CC1

nearest known ligand 0.75

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.75
KMT2A Q03164 5/20 0.68
MEN1 O00255 4/20 0.68
KDM4E B2RXH2 3/20 0.68
OPRM1 P35372 1/20 0.68
OPRD1 P41143 1/20 0.68
IGF1R P08069 3/20 0.57
ALDH1A1 P00352 1/20 0.57
PKM P14618 1/20 0.56
HTT P42858 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10746494 0.91 GAA (0.82) GAAKMT2AMEN1KDM4EOPRM1
SCHEMBL2796836 0.91 GAA (0.82) GAAKMT2AMEN1KDM4EOPRM1
SCHEMBL18704990 0.86 KMT2A (0.73) GAAKMT2AMEN1KDM4EOPRM1
Acetic Acid SCHEMBL9325415 0.86 GAA (0.75) GAAKMT2AMEN1KDM4EOPRM1
SCHEMBL352281 0.86 GAA (1.00) GAAKMT2AMEN1KDM4EOPRM1
SCHEMBL3976521 0.85 GAA (0.74) GAAKMT2AMEN1KDM4EOPRM1
SCHEMBL4466517 0.85 KMT2A (0.71) GAAKMT2AMEN1KDM4EOPRM1
SCHEMBL4474689 0.85 KMT2A (0.71) GAAKMT2AMEN1KDM4EOPRM1
SCHEMBL4477437 0.85 KMT2A (0.71) GAAKMT2AMEN1KDM4EOPRM1
SCHEMBL4486265 0.85 KMT2A (0.71) GAAKMT2AMEN1KDM4EOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022204065-A1 IRON(III) MACROCYCLIC COMPLEXES WITH MIXED HYROXYL PENDANTS AS MRI CONTRAST AGENTS THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2022-09-29 WO disclosed