SCHEMBL352281

SCHEMBL352281

CN1CCN(CC(O)c2ccccc2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 1.00
KMT2A Q03164 5/20 0.68
MEN1 O00255 4/20 0.68
KDM4E B2RXH2 4/20 0.68
OPRM1 P35372 1/20 0.68
OPRD1 P41143 1/20 0.68
IGF1R P08069 3/20 0.57
ALDH1A1 P00352 1/20 0.57
PKM P14618 1/20 0.56
HTT P42858 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31341343 0.95 GAA (0.90) GAAKMT2AMEN1KDM4EOPRM1
SCHEMBL10746494 0.91 GAA (0.82) GAAKMT2AMEN1KDM4EOPRM1
SCHEMBL2796836 0.91 GAA (0.82) GAAKMT2AMEN1KDM4EOPRM1
SCHEMBL24672691 0.86 GAA (0.75) GAAKMT2AMEN1KDM4EOPRM1
Acetic Acid SCHEMBL9325415 0.86 GAA (0.75) GAAKMT2AMEN1KDM4EOPRM1
SCHEMBL3976521 0.85 GAA (0.74) GAAKMT2AMEN1KDM4EOPRM1
SCHEMBL1461910 0.85 GAA (0.73) GAAKMT2AMEN1KDM4EOPRM1
SCHEMBL7428354 0.84 GAA (0.73) GAA
Hydrochloric Acid SCHEMBL10502374 0.84 GAA (0.73) GAAKMT2AMEN1KDM4EOPRM1
SCHEMBL1205842 0.83 GAA (0.71) GAAKMT2AMEN1KDM4EOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250179233-A1 PROCESS AND CATALYSTS FOR HYDROGEN MEDIATED ANIONIC COPOLYMERIZATION OF CONJUGATED DIENES AND LIQUID COPOLYMERS THEREOF ALBEMARLE CORPORATION (US) 2025-06-05 US claimed
EP-4486808-A2 PROCESS AND CATALYSTS FOR HYDROGEN MEDIATED ANIONIC COPOLYMERIZATION OF CONJUGATED DIENES AND LIQUID COPOLYMERS THEREOF ALBEMARLE CORPORATION (US) 2025-01-08 EP claimed
CN-119137172-A Process and catalyst for hydrogen-mediated anionic copolymerization of conjugated dienes and liquid copolymers thereof 雅宝公司 2024-12-13 CN claimed
WO-2023168218-A2 PROCESS AND CATALYSTS FOR HYDROGEN MEDIATED ANIONIC COPOLYMERIZATION OF CONJUGATED DIENES AND LIQUID COPOLYMERS THEREOF ALBEMARLE CORPORATION (US) 2023-09-07 WO claimed
US-20250179233-A1 PROCESS AND CATALYSTS FOR HYDROGEN MEDIATED ANIONIC COPOLYMERIZATION OF CONJUGATED DIENES AND LIQUID COPOLYMERS THEREOF ALBEMARLE CORPORATION (US) 2025-06-05 US disclosed
EP-4486808-A2 PROCESS AND CATALYSTS FOR HYDROGEN MEDIATED ANIONIC COPOLYMERIZATION OF CONJUGATED DIENES AND LIQUID COPOLYMERS THEREOF ALBEMARLE CORPORATION (US) 2025-01-08 EP disclosed
CN-119137172-A Process and catalyst for hydrogen-mediated anionic copolymerization of conjugated dienes and liquid copolymers thereof 雅宝公司 2024-12-13 CN disclosed
WO-2023168218-A2 PROCESS AND CATALYSTS FOR HYDROGEN MEDIATED ANIONIC COPOLYMERIZATION OF CONJUGATED DIENES AND LIQUID COPOLYMERS THEREOF ALBEMARLE CORPORATION (US) 2023-09-07 WO disclosed
EP-3322706-B1 SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS ARRAY BIOPHARMA INC (US) 2020-11-11 EP disclosed
WO-2018136661-A1 SUBSTITUTED PYRAZOLO[1,5-a]PYRAZINE COMPOUNDS AS RET KINASE INHIBITORS ANDREWS STEVEN W (US) 2018-07-26 WO disclosed
US-20180186796-A1 COMPOUNDS AND USES THEREOF LEAD DISCOVERY SIENA S.R.L. (IT) 2018-07-05 US disclosed
US-20180186796-A1 COMPOUNDS AND USES THEREOF LEAD DISCOVERY SIENA S.R.L. (IT) 2018-07-05 US disclosed
US-20150152045-A1 REACTIVE IONIC LIQUIDS BASF SE 2015-06-04 US disclosed
US-20120016124-A1 SEROTONIN REUPTAKE INHIBITORS BAYLOR UNIVERSITY (US) 2012-01-19 US disclosed
US-7893261-B2 bi-functional organic molecules which combine serotonin transporter reuptake inhibition with serotonin (5-HT, such as 5-HT2A) receptor antagonism in one molecular entity BAYLOR UNIVERSITY (US) 2011-02-22 US disclosed
US-20080214572-A1 Selected Tetracyclic Tetrahydrofuran Derivatives Containing a Cyclic Amine Side Chain FERNANDEZ-GADEA FRANCISCO JAVIER 2008-09-04 US disclosed
US-20080214572-A1 Selected Tetracyclic Tetrahydrofuran Derivatives Containing a Cyclic Amine Side Chain FERNANDEZ-GADEA FRANCISCO JAVIER 2008-09-04 US disclosed
US-20080132514-A1 Serotonin Reuptake Inhibitors BAYLOR UNIVERSITY 2008-06-05 US disclosed
EP-1732610-A2 TARGETED SEROTONIN REUPTAKE INHIBITORS BAYLOR UNIVERSITY (US) 2006-12-20 EP disclosed
WO-2005094896-A2 TARGETED SEROTONIN REUPTAKE INHIBITORS BAYLOR UNIVERSITY (US) 2005-10-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120016124-A1 SEROTONIN REUPTAKE INHIBITORS HTR2A, HTR2C, HTR1A GAA 3584/4885KMT2A 839/4885MEN1 4852/4885
US-20180186796-A1 COMPOUNDS AND USES THEREOF FYN, SRC, HCK GAA 2132/4885KMT2A 2777/4885MEN1 3464/4885
US-20150152045-A1 REACTIVE IONIC LIQUIDS INPPL1, PIK3CG, PTEN GAA 3797/4885KMT2A 1774/4885MEN1 1765/4885
US-20080132514-A1 Serotonin Reuptake Inhibitors HTR2A, HTR2C, HTR1A GAA 3584/4885KMT2A 839/4885MEN1 4852/4885
US-20080214572-A1 Selected Tetracyclic Tetrahydrofuran Derivatives Containing a Cyclic Amine Side Chain HTR2C, HTR2A, HTR5A GAA 3308/4885KMT2A 1784/4885MEN1 4384/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.