⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23945120 | 0.83 | — | — | |
| SCHEMBL25006291 | 0.83 | — | — | |
| SCHEMBL25108788 | 0.77 | LMNA (0.31) | — | |
| SCHEMBL24673660 | 0.77 | JAK2 (0.31) | — | |
| SCHEMBL25118225 | 0.77 | JAK2 (0.31) | — | |
| SCHEMBL25123195 | 0.73 | — | — | |
| SCHEMBL28930466 | 0.71 | LMNA (0.46) | — | |
| SCHEMBL26211774 | 0.71 | LMNA (0.35) | — | |
| SCHEMBL24052115 | 0.67 | — | — | |
| SCHEMBL25467349 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340570-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2022-10-27 | — | — | US | disclosed |