⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25474956 | 0.78 | — | — | |
| SCHEMBL2600751 | 0.72 | — | — | |
| SCHEMBL12245597 | 0.70 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL14326741 | 0.68 | — | — | |
| SCHEMBL17540833 | 0.60 | KDM4E (0.49) | — | |
| SCHEMBL12922239 | 0.57 | ALDH1A1 (0.31) | — | |
| SCHEMBL11292172 | 0.56 | — | — | |
| SCHEMBL13438489 | 0.56 | KDM4E (0.30) | — | |
| SCHEMBL15820692 | 0.55 | — | — | |
| SCHEMBL13054401 | 0.54 | GCGR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340570-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2022-10-27 | — | — | US | disclosed |