Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | GAA | P10253 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ERN1 | O75460 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4828411 | 0.82 | HSD17B10 (0.59) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL1325658 | 0.81 | HSD17B10 (0.63) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL31201820 | 0.81 | HSD17B10 (0.63) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL31187328 | 0.80 | HSD17B10 (0.34) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL10908287 | 0.79 | HSD17B10 (0.59) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL11622371 | 0.79 | KDM4E (0.61) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL226196 | 0.78 | HSD17B10 (0.76) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL29357214 | 0.78 | HSD17B10 (1.00) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL36762 | 0.78 | HSD17B10 (1.00) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL5236444 | 0.78 | HSD17B10 (0.40) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114736195-B | Oxathiolane-benzocoumarin compound, preparation method thereof and application of oxathiolane-benzocoumarin compound as fluorescent probe | 天水师范学院 | 2022-11-15 | — | — | CN | claimed |
| CN-114736195-A | Oxathiolane-benzocoumarin compound, preparation method thereof and application of oxathiolane-benzocoumarin compound as fluorescent probe | 天水师范学院 | 2022-07-12 | — | — | CN | claimed |
| CN-113480495-A | Ga (III) off-on type fluorescent probe and preparation method and application thereof | 温州市工业科学研究院 | 2021-10-08 | — | — | CN | claimed |
| CN-112955141-B | Improved method for inducing tissue regeneration and senescent cell lysis in mammalian cells | AGEX治疗公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-113728055-B | Curable composition, cured product layer, optical laminate, and image display device | 住友化学株式会社 | 2024-02-09 | — | — | CN | disclosed |
| CN-113748018-B | Optical laminate and image display device | 住友化学株式会社 | 2023-10-10 | — | — | CN | disclosed |
| CN-114736195-B | Oxathiolane-benzocoumarin compound, preparation method thereof and application of oxathiolane-benzocoumarin compound as fluorescent probe | 天水师范学院 | 2022-11-15 | — | — | CN | disclosed |
| CN-114736195-A | Oxathiolane-benzocoumarin compound, preparation method thereof and application of oxathiolane-benzocoumarin compound as fluorescent probe | 天水师范学院 | 2022-07-12 | — | — | CN | disclosed |
| CN-113480495-A | Ga (III) off-on type fluorescent probe and preparation method and application thereof | 温州市工业科学研究院 | 2021-10-08 | — | — | CN | disclosed |
| CN-112955141-A | Improved methods for inducing tissue regeneration and lysis of senescent cells in mammalian cells | AGEX治疗公司 | 2021-06-11 | — | — | CN | disclosed |
| EP-3322986-A1 | ALANINE-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | Arvinas, Inc. (US) | 2018-05-23 | — | — | EP | disclosed |
| WO-2017011590-A1 | ALANINE-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | Arvinas, Inc. (US) | 2017-01-19 | — | — | WO | disclosed |
| EP-2668160-A1 | TRPM8 RECEPTOR ANTAGONISTS | Dompe' S.p.A. (IT) | 2013-12-04 | — | — | EP | disclosed |
| WO-2012101244-A1 | TRPM8 RECEPTOR ANTAGONISTS | DOMPE' S.P.A. (IT) | 2012-08-02 | — | — | WO | disclosed |
| EP-2370422-A1 | THIOCHROMENE DERIVATIVES AS HIP HYDROXYLASE INHIBITORS | Fibrogen, Inc. (US) | 2011-10-05 | — | — | EP | disclosed |
| WO-2010056767-A1 | THIOCHROMENE DERIVATIVES AS HIP HYDROXYLASE INHIBITORS | FIBROGEN, INC. (US) | 2010-05-20 | — | — | WO | disclosed |
| EP-1474140-A1 | 2-OXAZOLAMINES AND THEIR USE AS 5-HT2B RECEPTOR ANTAGONISTS | Pharmagene Laboratories Ltd (GB) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003068226-A1 | 2-OXAZOLAMINES AND THEIR USE AS 5-HT2B RECEPTOR ANTAGONISTS | PHARMAGENE LABORATORIES LIMITED (GB) | 2003-08-21 | — | — | WO | disclosed |