Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6620341 | 0.82 | HSD17B10 (0.38) | HSD17B10CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL7924281 | 0.81 | HSD17B10 (0.40) | HSD17B10CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL15351705 | 0.79 | ALDH1A1 (0.44) | HSD17B10CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL2467403 | 0.78 | HSD17B10 (0.63) | HSD17B10CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL3414797 | 0.78 | CYP2A6 (0.48) | HSD17B10CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL9404144 | 0.76 | HTR2A (0.54) | HSD17B10CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8988212 | 0.76 | ALDH1A1 (0.46) | HSD17B10CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL7783948 | 0.75 | NCEH1 (0.45) | HSD17B10CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL18070730 | 0.75 | ALDH1A1 (0.44) | HSD17B10CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6403906 | 0.75 | ALDH1A1 (0.60) | HSD17B10CYP1A2CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772148-A | Imidazo [1,2-a ] pyrimidine matrine/sophoridine derivative, preparation method and application | 西北农林科技大学 | 2024-10-15 | — | — | CN | disclosed |
| EP-3322705-A1 | 2-AMINO-1,3,4-THIADIAZINE AND 2-AMINO-1,3,4-OXADIAZINE BASED ANTIFUNGAL AGENTS | F2G Limited (GB) | 2018-05-23 | — | — | EP | disclosed |
| WO-2017009651-A1 | 2-AMINO-1,3,4-THIADIAZINE AND 2-AMINO-1,3,4-OXADIAZINE BASED ANTIFUNGAL AGENTS | F2G LIMITED (GB) | 2017-01-19 | — | — | WO | disclosed |
| EP-1851232-A2 | DIHYDROIMIDAZOTHIAZOLE DERIVATIVES | Prosidion Limited (GB) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006085118-A2 | DIHYDROIMIDAZOTHIAZOLE DERIVATIVES | PROSIDION LIMITED (GB) | 2006-08-17 | — | — | WO | disclosed |
| EP-1474140-A1 | 2-OXAZOLAMINES AND THEIR USE AS 5-HT2B RECEPTOR ANTAGONISTS | Pharmagene Laboratories Ltd (GB) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003068226-A1 | 2-OXAZOLAMINES AND THEIR USE AS 5-HT2B RECEPTOR ANTAGONISTS | PHARMAGENE LABORATORIES LIMITED (GB) | 2003-08-21 | — | — | WO | disclosed |