Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28762184 | 0.82 | ROCK1 (0.48) | ROCK1DRD2MTNR1AMTNR1BGAA | |
| SCHEMBL14827764 | 0.80 | GAA (0.47) | ROCK1DRD2SIRT2MTNR1AMTNR1B | |
| SCHEMBL27675178 | 0.77 | ROCK1 (0.44) | ROCK1DRD2SIRT2MTNR1AMTNR1B | |
| SCHEMBL17560591 | 0.77 | DRD2 (0.49) | ROCK1DRD2SIRT2MTNR1AMTNR1B | |
| SCHEMBL2462174 | 0.77 | MAPT (0.57) | ROCK1DRD2MTNR1AMTNR1BGAA | |
| SCHEMBL1580384 | 0.77 | SNCA (0.38) | SIRT2GAALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL23579413 | 0.77 | ROCK1 (0.46) | ROCK1DRD2MTNR1AMTNR1BGAA | |
| SCHEMBL7832893 | 0.77 | ROCK1 (0.46) | ROCK1DRD2MTNR1AMTNR1BGAA | |
| SCHEMBL29974269 | 0.77 | ROCK1 (0.46) | ROCK1DRD2MTNR1AMTNR1BGAA | |
| SCHEMBL1990819 | 0.77 | ROCK1 (0.46) | ROCK1DRD2SIRT2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2542525-A1 | CATIONIC 6-AMINOINDOLINES, DYEING COMPOSITIONS CONTAINING THEM, PROCESSES AND USES THEREOF | L'Oréal (FR) | 2013-01-09 | — | — | EP | disclosed |
| WO-2011107501-A1 | CATIONIC 6-AMINOINDOLINES, DYEING COMPOSITIONS CONTAINING THEM, PROCESSES AND USES THEREOF | L'OREAL (FR) | 2011-09-09 | — | — | WO | disclosed |