Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 12/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.45 |
| ▸ | IKZF2 | Q9UKS7 | 3/20 | 0.44 |
| ▸ | WIZ | O95785 | 1/20 | 0.44 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29822942 | 1.00 | ESR1 (0.49) | ESR1CRBNDDB1GPR119IKZF2 | |
| SCHEMBL30906264 | 0.96 | ESR1 (0.53) | ESR1CRBNDDB1IKZF2WIZ | |
| SCHEMBL27314017 | 0.93 | CRBN (0.53) | ESR1CRBNDDB1IKZF2IKZF1 | |
| SCHEMBL30942356 | 0.92 | CRBN (0.57) | ESR1CRBNDDB1IKZF2WIZ | |
| SCHEMBL22581062 | 0.92 | CRBN (0.57) | ESR1CRBNDDB1IKZF2WIZ | |
| SCHEMBL34467151 | 0.92 | CRBN (0.54) | ESR1CRBNDDB1IKZF2 | |
| SCHEMBL30906233 | 0.92 | CRBN (0.56) | ESR1CRBNDDB1IKZF2WIZ | |
| SCHEMBL31129522 | 0.91 | CRBN (0.57) | ESR1CRBNDDB1IKZF2WIZ | |
| SCHEMBL30906205 | 0.90 | CRBN (0.55) | ESR1CRBNDDB1IKZF2WIZ | |
| SCHEMBL22581055 | 0.90 | CRBN (0.51) | ESR1CRBNDDB1IKZF2WIZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022159688-A9 | DEGRADERS OF GRK2 AND USES THEREOF | SONATA THERAPEUTICS, INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| WO-2022159688-A1 | DEGRADERS OF GRK2 AND USES THEREOF | CYGNAL THERAPEUTICS, INC. (US) | 2022-07-28 | — | — | WO | disclosed |