Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24674692 | 0.81 | — | — | |
| SCHEMBL24675551 | 0.79 | KMT2A (0.42) | TIPARPALDH1A1MDM2SCN10A | |
| SCHEMBL26958203 | 0.77 | TIPARP (0.48) | TIPARPLMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL24640749 | 0.75 | TIPARP (0.45) | TIPARP | |
| SCHEMBL24640355 | 0.75 | TIPARP (0.47) | TIPARPLMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL24675189 | 0.75 | TIPARP (0.45) | TIPARP | |
| SCHEMBL24675177 | 0.75 | TIPARP (0.45) | TIPARP | |
| SCHEMBL24640367 | 0.75 | TIPARP (0.47) | TIPARPLMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL24640010 | 0.73 | TIPARP (0.48) | TIPARPLMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL24639999 | 0.73 | TIPARP (0.48) | TIPARPLMNAALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022223022-A1 | FUSED-RING HETEROCYCLE DERIVATIVE AND MEDICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2022-10-27 | — | — | WO | disclosed |