Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 18/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2466696 | 0.97 | MET (0.55) | METHDAC1 | |
| SCHEMBL2468835 | 0.95 | MET (0.58) | METMEN1KMT2AHDAC1 | |
| SCHEMBL2466039 | 0.91 | MET (0.54) | MET | |
| SCHEMBL2468870 | 0.90 | MET (0.46) | METMEN1KMT2AHDAC1 | |
| SCHEMBL2468334 | 0.89 | MET (0.63) | MET | |
| SCHEMBL2464380 | 0.89 | MET (0.63) | MET | |
| SCHEMBL2497392 | 0.89 | MET (0.56) | METMEN1KMT2AHDAC1 | |
| SCHEMBL1951449 | 0.88 | MET (0.54) | METHDAC1 | |
| SCHEMBL2491089 | 0.88 | MET (0.59) | MET | |
| SCHEMBL2468084 | 0.88 | MET (0.54) | METMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960370-B1 | PYRIDIAZINONE DERIVATIVES FOR TUMOUR TREATMENT | MERCK PATENT GMBH (DE) | 2011-10-05 | — | — | EP | claimed |