Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 7/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24675011 | 0.82 | TIPARP (0.38) | SCN10ACYP2C9CYP2C19 | |
| SCHEMBL24675530 | 0.79 | TIPARP (0.41) | POLBSCN10ACYP2C9CYP2C19 | |
| SCHEMBL24674720 | 0.78 | — | — | |
| SCHEMBL24675540 | 0.76 | LCAT (0.34) | SCN10AALDH1A1 | |
| SCHEMBL26958160 | 0.74 | HTR2A (0.47) | HTR2AHTR2CHTR2BLMNASMN1; SMN2 | |
| SCHEMBL24674715 | 0.73 | HTR2C (0.61) | HTR2AHTR2CHTR2B | |
| SCHEMBL31244892 | 0.73 | HTR2C (0.61) | HTR2AHTR2CHTR2B | |
| SCHEMBL24675323 | 0.73 | HTR2C (0.61) | HTR2AHTR2CHTR2B | |
| SCHEMBL24675551 | 0.71 | KMT2A (0.42) | POLBSCN10AALDH1A1 | |
| SCHEMBL24674967 | 0.71 | TIPARP (0.40) | LMNASMN1; SMN2SCN10AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022223022-A1 | FUSED-RING HETEROCYCLE DERIVATIVE AND MEDICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2022-10-27 | — | — | WO | disclosed |