Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18398793 | 0.78 | CHRNA3 (0.46) | LTA4HCHRNA3CHRNB4CHRNB2CHRNA4 | |
| SCHEMBL23174270 | 0.77 | CHRNA3 (0.36) | LTA4HCHRNA3CHRNB4CHRNB2CHRNA4 | |
| SCHEMBL5021487 | 0.77 | — | — | |
| SCHEMBL25883074 | 0.77 | CHRNA3 (0.44) | LTA4HCHRNA3CHRNB4CHRNB2CHRNA4 | |
| SCHEMBL10273859 | 0.77 | CHRNA3 (0.44) | LTA4HCHRNA3CHRNB4CHRNB2CHRNA4 | |
| SCHEMBL27521887 | 0.77 | — | — | |
| SCHEMBL10273868 | 0.77 | CHRNA3 (0.44) | LTA4HCHRNA3CHRNB4CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL27806461 | 0.76 | CHRNA3 (0.40) | LTA4HCHRNA3CHRNB4CHRNB2CHRNA4 | |
| SCHEMBL6416529 | 0.75 | — | — | |
| SCHEMBL24674661 | 0.74 | CHRNA3 (0.38) | LTA4HCHRNA3CHRNB4CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022223022-A1 | FUSED-RING HETEROCYCLE DERIVATIVE AND MEDICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2022-10-27 | — | — | WO | disclosed |