Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 20/20 | 0.45 |
| ▸ | CDK2 | P24941 | 20/20 | 0.45 |
| ▸ | CDK1 | P06493 | 15/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 15/20 | 0.45 |
| ▸ | CCND1 | P24385 | 13/20 | 0.45 |
| ▸ | CDK6 | Q00534 | 13/20 | 0.45 |
| ▸ | CDK4 | P11802 | 12/20 | 0.45 |
| ▸ | CCND3 | P30281 | 12/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 6/20 | 0.45 |
| ▸ | CDK7 | P50613 | 6/20 | 0.45 |
| ▸ | CDK9 | P50750 | 6/20 | 0.45 |
| ▸ | CCNH | P51946 | 6/20 | 0.45 |
| ▸ | MNAT1 | P51948 | 6/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24676759 | 0.90 | CDK2 (0.51) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL24676438 | 0.90 | CCNE1 (0.46) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL24676437 | 0.89 | CCNE1 (0.50) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL29754923 | 0.87 | CCNE1 (0.48) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL24676821 | 0.87 | CCNE1 (0.48) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL29754879 | 0.86 | CCNE1 (0.47) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL24676443 | 0.86 | CCNE1 (0.47) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL24676458 | 0.83 | IKBKB (0.49) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL24676854 | 0.82 | CCNE1 (0.49) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL29754876 | 0.82 | CCNE1 (0.49) | CCNE1CDK2CDK1CCNB1CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155941-A1 | CDK2 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2022-07-28 | — | — | WO | disclosed |