Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 20/20 | 0.50 |
| ▸ | CDK2 | P24941 | 20/20 | 0.50 |
| ▸ | CDK1 | P06493 | 13/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 13/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.50 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.50 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.50 |
| ▸ | CCND1 | P24385 | 12/20 | 0.45 |
| ▸ | CDK6 | Q00534 | 12/20 | 0.45 |
| ▸ | CDK4 | P11802 | 9/20 | 0.45 |
| ▸ | CCND3 | P30281 | 9/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.43 |
| ▸ | CDK9 | P50750 | 3/20 | 0.43 |
| ▸ | CDK7 | P50613 | 2/20 | 0.43 |
| ▸ | CCNH | P51946 | 2/20 | 0.43 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24676759 | 0.91 | CDK2 (0.51) | CCNE1CDK2CDK1CCNB1CCNB2 | |
| SCHEMBL24676446 | 0.89 | CCNE1 (0.45) | CCNE1CDK2CDK1CCNB1CCNB2 | |
| SCHEMBL29754779 | 0.87 | CCNE1 (0.54) | CCNE1CDK2CDK1CCNB1CCNB2 | |
| SCHEMBL29754957 | 0.85 | CCNE1 (0.53) | CCNE1CDK2CDK1CCNB1CCNB2 | |
| SCHEMBL24676767 | 0.85 | CCNE1 (0.54) | CCNE1CDK2CDK1CCNB1CCNB2 | |
| SCHEMBL24676458 | 0.84 | IKBKB (0.49) | CCNE1CDK2CDK1CCNB1CCND1 | |
| SCHEMBL24676019 | 0.82 | CCNE1 (0.56) | CCNE1CDK2CDK1CCNB1CCNB2 | |
| SCHEMBL24676833 | 0.82 | CDK2 (0.52) | CCNE1CDK2CDK1CCNB1CCNB2 | |
| SCHEMBL24676994 | 0.81 | CDK2 (0.53) | CCNE1CDK2CDK1CCNB1CCNB2 | |
| SCHEMBL24676665 | 0.80 | GPR119 (0.40) | CCNE1CDK2CDK1CCNB1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155941-A1 | CDK2 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2022-07-28 | — | — | WO | disclosed |