Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 16/20 | 0.52 |
| ▸ | PPARA | Q07869 | 13/20 | 0.52 |
| ▸ | PPARG | P37231 | 9/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2466344 | 0.90 | PPARD (0.51) | PPARDPPARAPPARGFFAR1MAPT | |
| SCHEMBL2466100 | 0.90 | PPARD (0.54) | PPARDPPARAPPARGFFAR1MAPT | |
| SCHEMBL1765890 | 0.86 | PPARD (0.53) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL2467686 | 0.86 | PPARG (0.40) | PPARDPPARAPPARG | |
| SCHEMBL2466324 | 0.86 | PPARA (0.59) | PPARDPPARAPPARGMAPT | |
| SCHEMBL24742413 | 0.85 | PPARD (0.45) | PPARDPPARAPPARGFFAR1MAPT | |
| SCHEMBL12732425 | 0.85 | PPARD (0.45) | PPARDPPARAPPARGFFAR1MAPT | |
| SCHEMBL2462549 | 0.85 | PPARD (0.51) | PPARDPPARAPPARGFFAR1MAPT | |
| SCHEMBL12732443 | 0.84 | PPARD (0.51) | PPARDPPARAPPARGFFAR1MAPT | |
| SCHEMBL24742450 | 0.84 | PPARD (0.48) | PPARDPPARAPPARGFFAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1424330-B1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-RESPONSIVE RECEPTOR DELTA | NIPPON CHEMIPHAR CO (JP) | 2011-09-28 | — | — | EP | disclosed |