Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.40 |
| ▸ | PPARD | Q03181 | 5/20 | 0.40 |
| ▸ | PPARA | Q07869 | 7/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2466103 | 0.91 | PPARD (0.41) | PPARGPPARDPPARAS1PR1PTGDR2 | |
| SCHEMBL2466352 | 0.90 | PPARD (0.40) | PPARGPPARDPPARAS1PR1PTGDR2 | |
| SCHEMBL1765892 | 0.87 | PTGDR2 (0.40) | PPARGPPARDPPARAS1PR1PTGDR2 | |
| SCHEMBL2466327 | 0.86 | PPARA (0.45) | PPARGPPARDPPARAS1PR1CTSA | |
| SCHEMBL2467681 | 0.86 | PPARD (0.52) | PPARGPPARDPPARA | |
| SCHEMBL2462553 | 0.85 | PPARD (0.39) | PPARGPPARDPPARAS1PR1PRSS1 | |
| SCHEMBL2464421 | 0.83 | PPARD (0.45) | PPARGPPARDPPARAS1PR1PTGDR2 | |
| SCHEMBL2463460 | 0.83 | PPARD (0.53) | PPARGPPARDPPARAPTGDR2 | |
| SCHEMBL2465182 | 0.82 | PPARD (0.47) | PPARGPPARDPPARAS1PR1PTGDR2 | |
| SCHEMBL2467481 | 0.81 | PPARD (0.38) | PPARGPPARDPPARAS1PR1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1424330-B1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-RESPONSIVE RECEPTOR DELTA | NIPPON CHEMIPHAR CO (JP) | 2011-09-28 | — | — | EP | disclosed |