Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.43 |
| ▸ | SPR | P35270 | 5/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21285788 | 0.82 | HSD11B1 (0.69) | HSD11B1USP30SPR | |
| SCHEMBL13738053 | 0.82 | HSD11B1 (0.62) | HSD11B1USP30SPRKDM4DPDE10A | |
| SCHEMBL3296587 | 0.82 | HSD11B1 (0.62) | HSD11B1MCHR1USP30SPRKDM4D | |
| SCHEMBL5242729 | 0.82 | HSD11B1 (0.62) | HSD11B1USP30SPRKDM4DPDE10A | |
| SCHEMBL5845677 | 0.81 | HSD11B1 (0.58) | HSD11B1USP30SPRKDM4DPDE10A | |
| SCHEMBL18701755 | 0.81 | HSD11B1 (0.60) | HSD11B1USP30SPRKDM4DPDE10A | |
| SCHEMBL10223184 | 0.81 | HSD11B1 (0.60) | HSD11B1USP30SPRKDM4DPDE10A | |
| SCHEMBL15721133 | 0.80 | HSD11B1 (0.59) | HSD11B1USP30SPRKDM4DPDE10A | |
| SCHEMBL15721134 | 0.80 | HSD11B1 (0.59) | HSD11B1USP30SPRKDM4DPDE10A | |
| SCHEMBL14521695 | 0.78 | HSD11B1 (0.58) | HSD11B1USP30SPRHRH3KDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155941-A1 | CDK2 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2022-07-28 | — | — | WO | disclosed |
| WO-2022155941-A1 | CDK2 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2022-07-28 | — | — | WO | disclosed |