Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 16/20 | 0.49 |
| ▸ | CDK1 | P06493 | 10/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 8/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.49 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.49 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.49 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.49 |
| ▸ | CDK4 | P11802 | 11/20 | 0.47 |
| ▸ | CCND1 | P24385 | 11/20 | 0.47 |
| ▸ | CDK6 | Q00534 | 6/20 | 0.47 |
| ▸ | CCND3 | P30281 | 5/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.41 |
| ▸ | CASK | O14936 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24677048 | 0.92 | CDK2 (0.48) | CDK2CDK1CCNE1CCNB1CDK5 | |
| SCHEMBL24675966 | 0.85 | CDK2 (0.60) | CDK2CDK1CCNE1CCNB1CDK5 | |
| SCHEMBL24676788 | 0.82 | CDK2 (0.56) | CDK2CDK1CCNE1CCNB1CDK5 | |
| SCHEMBL24675964 | 0.80 | CDK2 (0.59) | CDK2CDK1CCNE1CCNB1CDK5 | |
| SCHEMBL24676776 | 0.79 | CDK2 (0.61) | CDK2CDK1CCNE1CCNB1CDK5 | |
| SCHEMBL25402367 | 0.79 | CDK2 (0.63) | CDK2CDK1CCNE1CCNB1CDK5 | |
| SCHEMBL30537172 | 0.79 | CDK2 (0.63) | CDK2CDK1CCNE1CCNB1CDK5 | |
| SCHEMBL24676839 | 0.79 | CDK2 (0.58) | CDK2CDK1CCNE1CCNB1CDK5 | |
| SCHEMBL24675980 | 0.79 | CDK2 (0.59) | CDK2CDK1CCNE1CCNB1CDK5 | |
| SCHEMBL24676713 | 0.79 | MAP3K14 (0.35) | CDK2CDK4CCND1CDK6CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155941-A1 | CDK2 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2022-07-28 | — | — | WO | disclosed |