Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.35 |
| ▸ | CCND1 | P24385 | 3/20 | 0.34 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.34 |
| ▸ | CDK4 | P11802 | 2/20 | 0.34 |
| ▸ | CCND3 | P30281 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24676714 | 0.90 | DYRK2 (0.35) | MAP3K14USP30CCND1CDK6CDK4 | |
| SCHEMBL24676850 | 0.79 | CDK2 (0.49) | CCND1CDK6CDK4CCND3DYRK2 | |
| SCHEMBL30926175 | 0.75 | GPR119 (0.41) | TRPV3GPR119 | |
| SCHEMBL24676013 | 0.75 | PAX8 (0.33) | USP30 | |
| SCHEMBL24675999 | 0.74 | CDK1 (0.33) | CCND1CDK6CDK4CCND3CCNT1 | |
| SCHEMBL24676849 | 0.72 | NR1H2 (0.39) | USP30PIK3CA | |
| SCHEMBL17196760 | 0.72 | PIK3CD (0.38) | USP30CYP3A4CYP3A5GPR119 | |
| SCHEMBL17196879 | 0.72 | PIK3CD (0.44) | GPR119 | |
| SCHEMBL29611764 | 0.72 | GRM1 (0.53) | CDK9GPR119 | |
| SCHEMBL25297123 | 0.71 | POLB (0.43) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155941-A1 | CDK2 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2022-07-28 | — | — | WO | disclosed |