SCHEMBL24677027

SCHEMBL24677027

CC(C)(C)[Si](C)(C)OC1CCC[C@H]1N

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PPM1D O15297 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12629186 1.00 PPM1D (0.34) PPM1D
SCHEMBL30152746 1.00 PPM1D (0.34) PPM1D
SCHEMBL29754849 1.00 PPM1D (0.34) PPM1D
SCHEMBL31748003 1.00 PPM1D (0.34) PPM1D
SCHEMBL3735009 0.96 THRB (0.35) PPM1D
SCHEMBL20696859 0.96 THRB (0.35) PPM1D
SCHEMBL21307043 0.96 THRB (0.35) PPM1D
SCHEMBL3735003 0.96 THRB (0.35) PPM1D
SCHEMBL3735012 0.96 THRB (0.35) PPM1D
SCHEMBL7261027 0.96 THRB (0.35) PPM1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022272248-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2022-12-29 WO disclosed
WO-2022155941-A1 CDK2 INHIBITORS QILU REGOR THERAPEUTICS INC. (CN) 2022-07-28 WO disclosed