Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | PDCD1LG2 | Q9BQ51 | 6/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.34 |
| ▸ | FEN1 | P39748 | 4/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2468807 | 0.91 | MEP1B (0.36) | PDCD1LG2CD274ALOX5APFEN1 | |
| SCHEMBL2468810 | 0.90 | PDCD1LG2 (0.33) | ADORA2AADORA1ADORA3ADORA2BPDCD1LG2 | |
| SCHEMBL2462838 | 0.90 | PDCD1LG2 (0.36) | ADORA2APDCD1LG2CD274ALOX5APFEN1 | |
| SCHEMBL2468381 | 0.88 | ALOX5AP (0.47) | PDCD1LG2CD274ALOX5APFEN1MAPK8 | |
| SCHEMBL2466407 | 0.87 | PDCD1LG2 (0.35) | ADORA2AADORA1ADORA3ADORA2BPDCD1LG2 | |
| SCHEMBL2467890 | 0.87 | PDCD1LG2 (0.39) | ADORA2APDCD1LG2CD274 | |
| SCHEMBL2467010 | 0.86 | CD274 (0.41) | PDCD1LG2CD274 | |
| SCHEMBL2465857 | 0.86 | ALOX5AP (0.39) | PDCD1LG2CD274ALOX5APFEN1MAPT | |
| SCHEMBL2467061 | 0.86 | SCN10A (0.33) | ADORA2AADORA1PDCD1LG2CD274MAPK8 | |
| SCHEMBL2470794 | 0.86 | PDCD1LG2 (0.34) | ADORA2AADORA1PDCD1LG2CD274CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2939540-A1 | HERBICIDE SAFENER COMBINATION | Bayer Intellectual Property GmbH (DE) | 2015-11-04 | — | — | EP | disclosed |
| EP-2939541-A1 | HERBICIDE SAFENER COMBINATION | Bayer Intellectual Property GmbH (DE) | 2015-11-04 | — | — | EP | disclosed |
| EP-2369929-A2 | HERBICIDE-SAFENER COMBINATION | Bayer CropScience AG (DE) | 2011-10-05 | — | — | EP | disclosed |
| WO-2010060581-A2 | HERBICIDE-SAFENER COMBINATION | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | WO | disclosed |
| EP-2191719-A1 | Herbicide safener combination | Bayer CropScience AG (DE) | 2010-06-02 | — | — | EP | disclosed |