SCHEMBL24677673

SCHEMBL24677673

CNC(=O)C(N)CCCCNN

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ DPP7 Q9UHL4 6/20 0.49
▸ GNAI3 P08754 1/20 0.46
▸ GNAO1 P09471 1/20 0.46
▸ GNAI1 P63096 1/20 0.46
▸ RRM1 P23921 1/20 0.41
▸ SLC15A1 P46059 1/20 0.41
▸ ALOX15 P16050 1/20 0.39
▸ DPP8 Q6V1X1 4/20 0.38
▸ DPP9 Q86TI2 4/20 0.38
▸ DPP4 P27487 3/20 0.38
▸ GSR P00390 1/20 0.35
▸ MMP2 P08253 6/20 0.35
▸ MMP3 P08254 6/20 0.35
▸ MMP1 P03956 4/20 0.35
▸ MMP7 P09237 1/20 0.35
▸ SPHK1 Q9NYA1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16882307 0.86 DPP7 (0.50) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL8403553 0.83 DPP7 (0.48) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL20705075 0.81 DPP7 (0.54) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL20705091 0.81 DPP7 (0.54) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL8163475 0.81 DPP7 (0.54) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL15959310 0.81 DPP7 (0.50) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL20705089 0.81 DPP7 (0.54) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL20705077 0.81 DPP7 (0.54) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL13555514 0.81 DPP7 (0.46) DPP7GNAI3GNAO1GNAI1RRM1
SCHEMBL20414881 0.81 DPP7 (0.54) DPP7GNAI3GNAO1GNAI1RRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220273807-A1 CONJUGATES FOR USE IN METHODS OF TREATING CANCER ASTRAZENECA AB (SE) 2022-09-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220273807-A1 CONJUGATES FOR USE IN METHODS OF TREATING CANCER CD44, FOLH1, SLC17A5 DPP7 1481/4885GNAI3 2268/4885GNAO1 2556/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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