SCHEMBL24677731

SCHEMBL24677731

CC(=O)C1CN(C)C(=O)CN1C

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 7/20 0.38
ACE P12821 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL48990 0.75
SCHEMBL10037219 0.75
SCHEMBL21515905 0.71 MMP2 (0.40)
SCHEMBL12401915 0.71 MMP2 (0.40)
SCHEMBL22578791 0.70 BRD4 (0.38) BRD4
SCHEMBL11890794 0.69
SCHEMBL25811046 0.68 BRD4 (0.36) BRD4
SCHEMBL13865299 0.68 MAPK1 (0.32)
SCHEMBL13803892 0.67 BRD4 (0.63) BRD4
SCHEMBL14372529 0.67 BRD4 (0.63) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022188819-A1 SOS1 PROTEOLYSIS MODULATOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 苏州泽璟生物制药股份有限公司 2022-09-15 WO disclosed