⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24677733 | 0.74 | — | — | |
| SCHEMBL25811025 | 0.74 | — | — | |
| SCHEMBL24677748 | 0.74 | CHRNB2 (0.31) | — | |
| SCHEMBL25811027 | 0.71 | — | — | |
| SCHEMBL24677744 | 0.69 | — | — | |
| SCHEMBL19785072 | 0.63 | — | — | |
| SCHEMBL28288874 | 0.61 | — | — | |
| SCHEMBL9037558 | 0.61 | — | — | |
| SCHEMBL20676910 | 0.60 | CYP2D6 (0.41) | — | |
| SCHEMBL19401459 | 0.60 | CYP2D6 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022188819-A1 | SOS1 PROTEOLYSIS MODULATOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 苏州泽璟生物制药股份有限公司 | 2022-09-15 | — | — | WO | disclosed |