Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 4/20 | 0.43 |
| ▸ | AXL | P30530 | 3/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 5/20 | 0.37 |
| ▸ | CCNK | O75909 | 3/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | CHUK | O15111 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | PAK4 | O96013 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30084234 | 1.00 | PRKCI (0.43) | PRKCIAXLNUDT1CCNKCDK12 | |
| SCHEMBL24678194 | 0.85 | PRKCI (0.54) | PRKCIAXLNUDT1CCNKCDK12 | |
| SCHEMBL30084188 | 0.85 | PRKCI (0.54) | PRKCIAXLNUDT1CCNKCDK12 | |
| SCHEMBL30084285 | 0.84 | PRKCI (0.41) | PRKCIAXLNUDT1CCNKCDK12 | |
| SCHEMBL24678651 | 0.84 | PRKCI (0.41) | PRKCIAXLNUDT1CCNKCDK12 | |
| SCHEMBL24678163 | 0.84 | PRKCI (0.48) | PRKCIAXLNUDT1CCNKCDK12 | |
| SCHEMBL30084255 | 0.84 | PRKCI (0.48) | PRKCIAXLNUDT1CCNKCDK12 | |
| SCHEMBL24678196 | 0.84 | PRKCI (0.43) | PRKCIAXLNUDT1CCNKCDK12 | |
| SCHEMBL30084265 | 0.84 | PRKCI (0.43) | PRKCIAXLNUDT1CCNKCDK12 | |
| SCHEMBL24678723 | 0.81 | PRKCI (0.50) | PRKCIAXLNUDT1CCNKCDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022247676-A1 | COMPOUND WITH DIPYRROLOPYRIDINE STRUCTURE, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 南京康屹生物医药中心(有限合伙) | 2022-12-01 | — | — | WO | disclosed |
| CN-115385911-A | Compound with dipyrrolopyridine structure, preparation method and medical application | 南京康屹生物医药中心(有限合伙) | 2022-11-25 | — | — | CN | disclosed |
| CN-113292561-A | Compound with dipyrrolopyridine structure, preparation method and medical application | 中国药科大学 | 2021-08-24 | — | — | CN | disclosed |