Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 2/20 | 0.47 |
| ▸ | PRKCI | P41743 | 2/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30084217 | 1.00 | AXL (0.47) | AXLPRKCICSNK1DMAPK14AAK1 | |
| SCHEMBL24678675 | 0.88 | AXL (0.48) | AXLPRKCICSNK1DMAPK14AAK1 | |
| SCHEMBL30084219 | 0.88 | AXL (0.48) | AXLPRKCICSNK1DMAPK14AAK1 | |
| SCHEMBL30084262 | 0.86 | PRKCI (0.49) | AXLPRKCICSNK1DMAPK14AAK1 | |
| SCHEMBL24678613 | 0.86 | PRKCI (0.49) | AXLPRKCICSNK1DMAPK14AAK1 | |
| SCHEMBL24678728 | 0.83 | AXL (0.46) | AXLPRKCICSNK1DMAPK14AAK1 | |
| SCHEMBL30084172 | 0.83 | AXL (0.46) | AXLPRKCICSNK1DMAPK14AAK1 | |
| SCHEMBL24678159 | 0.83 | AXL (0.46) | AXLPRKCICSNK1DMAPK14AAK1 | |
| SCHEMBL30084167 | 0.83 | AXL (0.46) | AXLPRKCICSNK1DMAPK14AAK1 | |
| SCHEMBL24678406 | 0.82 | AXL (0.48) | AXLPRKCIAAK1NUDT1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022247676-A1 | COMPOUND WITH DIPYRROLOPYRIDINE STRUCTURE, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 南京康屹生物医药中心(有限合伙) | 2022-12-01 | — | — | WO | disclosed |
| CN-115385911-A | Compound with dipyrrolopyridine structure, preparation method and medical application | 南京康屹生物医药中心(有限合伙) | 2022-11-25 | — | — | CN | disclosed |
| CN-113292561-A | Compound with dipyrrolopyridine structure, preparation method and medical application | 中国药科大学 | 2021-08-24 | — | — | CN | disclosed |