Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 7/20 | 0.36 |
| ▸ | PPARG | P37231 | 5/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 9/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2467448 | 0.92 | PPARD (0.43) | THRATHRBPPARAPPARGPPARD | |
| SCHEMBL2463832 | 0.87 | PPARA (0.39) | THRATHRBPPARAPPARGPPARD | |
| SCHEMBL6888377 | 0.86 | THRA (0.38) | THRATHRBPPARAPPARGPPARD | |
| SCHEMBL2460829 | 0.86 | PPARA (0.42) | THRATHRBPPARAPPARGPPARD | |
| SCHEMBL2465204 | 0.84 | PPARD (0.46) | PPARAPPARGPPARDMEN1ALDH1A1 | |
| SCHEMBL2465706 | 0.83 | PPARA (0.39) | THRATHRBPPARAPPARGPPARD | |
| SCHEMBL2463129 | 0.81 | PPARA (0.42) | THRATHRBPPARAPPARGPPARD | |
| SCHEMBL2467445 | 0.79 | PPARD (0.59) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL12732402 | 0.79 | PPARD (0.52) | PPARAPPARGPPARDMAPTFFAR1 | |
| SCHEMBL2468793 | 0.79 | PPARD (0.56) | PPARAPPARGPPARDMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1424330-B1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-RESPONSIVE RECEPTOR DELTA | NIPPON CHEMIPHAR CO (JP) | 2011-09-28 | — | — | EP | disclosed |