Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 17/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 17/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 14/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2082 | 0.99 | KCNH2 (0.66) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL19772441 | 0.85 | SLC6A4 (0.68) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL8042323 | 0.83 | SLC6A4 (0.91) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| Hydrochloric Acid SCHEMBL2241 | 0.82 | SLC6A4 (0.60) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| Hydrochloric Acid SCHEMBL2216 | 0.82 | KCNH2 (0.91) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| Hydrochloric Acid SCHEMBL10838881 | 0.81 | KCNH2 (0.59) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| Hydrochloric Acid SCHEMBL10838493 | 0.81 | KCNH2 (0.59) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL10839800 | 0.80 | SLC6A4 (0.59) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL10839053 | 0.80 | SLC6A3 (0.55) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| Hydrochloric Acid SCHEMBL10840145 | 0.80 | SLC6A2 (0.60) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814352-A | ANTIDEPRESSANT CYCLOBUTYL BENZYLAMINE | THE BOOTS COMPANY PLC (GB) | 1989-03-21 | — | — | US | disclosed |
| US-4806570-A | ANTIDEPRESSANTS | THE BOOTS COMPANY PLC (GB) | 1989-02-21 | — | — | US | disclosed |
| US-4767790-A | ANTIDEPRESSANTS | THE BOOTS COMPANY PLC (GB) | 1988-08-30 | — | — | US | disclosed |
| US-4746680-A | ANTIDEPRESSANTS | THE BOOTS COMPANY P.L.C. (GB) | 1988-05-24 | — | — | US | disclosed |
| US-4522828-A | CYCLOBUTYLALKYLAMINE COMPOUNDS, ANTIDEPRESSANTS | THE BOOTS COMPANY PLC (GB) | 1985-06-11 | — | — | US | disclosed |