Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 10/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.30 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.30 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679480 | 0.77 | AKR1C3 (0.44) | AKR1C3APEX1 | |
| SCHEMBL6136900 | 0.77 | AKR1C3 (0.44) | AKR1C3APEX1 | |
| SCHEMBL8956732 | 0.75 | AKR1C3 (0.39) | AKR1C3APEX1 | |
| SCHEMBL2476870 | 0.70 | AKR1C3 (0.41) | AKR1C3APEX1 | |
| SCHEMBL1225040 | 0.69 | HCAR2 (0.38) | APEX1 | |
| SCHEMBL154779 | 0.68 | AKR1C3 (0.42) | AKR1C3APEX1 | |
| SCHEMBL29199596 | 0.68 | AKR1C3 (0.39) | AKR1C3APEX1 | |
| SCHEMBL157888 | 0.67 | AKR1C3 (0.41) | AKR1C3APEX1 | |
| SCHEMBL2937034 | 0.67 | AKR1C3 (0.41) | AKR1C3APEX1 | |
| SCHEMBL156064 | 0.66 | AKR1C3 (0.40) | AKR1C3APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4777515-B2 | — | — | 2011-09-21 | — | — | JP | claimed |
| EP-1124950-B1 | Morpholino based p53 antisense oligonucleotide, and uses thereof | AVI BIOPHARMA INC (US) | 2006-07-12 | — | — | EP | claimed |
| JP-2002528464-A | — | — | 2002-09-03 | — | — | JP | claimed |
| US-6365577-B1 | p53 antisense agent and method | AVI BIOPHARMA, INC. | 2002-04-02 | — | — | US | claimed |
| EP-1124950-A2 | p53 ANTISENSE AGENT AND METHOD | Avi Biopharma, Inc. (US) | 2001-08-22 | — | — | EP | claimed |
| WO-2000024885-A2 | p53 MORPHOLINO-BASED ANTISENSE | AVI BIOPHARMA, INC. (US) | 2000-05-04 | — | — | WO | claimed |
| EP-1124950-B1 | Morpholino based p53 antisense oligonucleotide, and uses thereof | AVI BIOPHARMA INC (US) | 2006-07-12 | — | — | EP | disclosed |
| US-6365577-B1 | p53 antisense agent and method | AVI BIOPHARMA, INC. | 2002-04-02 | — | — | US | disclosed |
| EP-1124950-A2 | p53 ANTISENSE AGENT AND METHOD | Avi Biopharma, Inc. (US) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000024885-A2 | p53 MORPHOLINO-BASED ANTISENSE | AVI BIOPHARMA, INC. (US) | 2000-05-04 | — | — | WO | disclosed |