Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12334763 | 0.73 | GAA (0.52) | GAAHTTTSHRPOLBSMN1; SMN2 | |
| SCHEMBL5031121 | 0.73 | GAA (0.47) | GAASMN1; SMN2LMNAALDH1A1MAPK1 | |
| SCHEMBL22720076 | 0.72 | GAA (0.47) | GAAHTTTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL84372 | 0.72 | TSHR (0.62) | GAAHTTTSHRPOLBSMN1; SMN2 | |
| SCHEMBL31733069 | 0.71 | CYP3A4 (0.44) | GAAHTTTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL12334776 | 0.70 | GAA (0.49) | GAAHTTTSHRPOLBSMN1; SMN2 | |
| SCHEMBL11396784 | 0.69 | SMN1; SMN2 (0.46) | GAAHTTTSHRPOLBSMN1; SMN2 | |
| SCHEMBL13825940 | 0.69 | GAA (0.60) | GAAHTTTSHRSMN1; SMN2ALDH1A1 | |
| Dimethylamine SCHEMBL27882636 | 0.68 | TSHR (0.57) | GAAHTTTSHRPOLBSMN1; SMN2 | |
| SCHEMBL20216179 | 0.68 | MAPK1 (0.46) | GAAHTTTSHRPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022188729-A1 | FUSED RING DERIVATIVES USEFUL AS KRAS G12D INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-09-15 | — | — | WO | disclosed |