Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24683218 | 0.89 | ESR1 (0.40) | MAPTPKMKDM4EHSP90AA1ESR1 | |
| SCHEMBL29800041 | 0.87 | MAPT (0.43) | MAPTALDH1A1PKMGAADYRK1A | |
| SCHEMBL24682178 | 0.87 | MAPT (0.43) | MAPTALDH1A1PKMGAADYRK1A | |
| SCHEMBL24683889 | 0.84 | MAPK8 (0.40) | LMNAMAPK1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL29800050 | 0.81 | MAPT (0.42) | MAPTALDH1A1PKMGAALMNA | |
| SCHEMBL24683885 | 0.81 | MAPT (0.42) | MAPTALDH1A1PKMGAALMNA | |
| SCHEMBL29799959 | 0.77 | ESR1 (0.43) | MAPTALDH1A1PKMGAAKDM4E | |
| SCHEMBL24683189 | 0.77 | ESR1 (0.43) | MAPTALDH1A1PKMGAAKDM4E | |
| SCHEMBL24682174 | 0.77 | TSPO (0.44) | DYRK1AMEN1KMT2AESR1ESR2 | |
| SCHEMBL29799804 | 0.77 | TSPO (0.44) | DYRK1AMEN1KMT2AESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022173329-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | Акционерное общество "Отисифарм" | 2022-08-18 | — | — | WO | disclosed |