SCHEMBL24684

SCHEMBL24684

CCNc1cc([N+](=O)[O-])cc(Cl)c1O

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 1/20 0.54
PDPK1 O15530 1/20 0.47
CYTH3 O43739 1/20 0.47
AKT1 P31749 1/20 0.47
ALDH1A1 P00352 3/20 0.46
MAPT P10636 3/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
LMNA P02545 1/20 0.43
HTT P42858 1/20 0.43
GAA P10253 1/20 0.43
PKM P14618 1/20 0.43
PGK1 P00558 1/20 0.41
HCAR3 P49019 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27525505 1.00 GPR35 (0.54) GPR35PDPK1CYTH3AKT1ALDH1A1
SCHEMBL3417277 0.92 GPR35 (0.47) GPR35PDPK1CYTH3AKT1ALDH1A1
SCHEMBL15286795 0.89 GPR35 (0.44) GPR35PDPK1CYTH3AKT1ALDH1A1
SCHEMBL9359949 0.88 GPR35 (0.51) GPR35PDPK1CYTH3AKT1ALDH1A1
Nitrobenzene SCHEMBL27786573 0.85 PDPK1 (0.47) GPR35PDPK1CYTH3AKT1ALDH1A1
SCHEMBL9359770 0.84 GPR35 (0.50) GPR35PDPK1CYTH3AKT1ALDH1A1
SCHEMBL9359735 0.84 GPR35 (0.50) GPR35PDPK1CYTH3AKT1ALDH1A1
SCHEMBL4807504 0.83 GPR35 (0.53) GPR35PDPK1CYTH3AKT1ALDH1A1
SCHEMBL453875 0.83 GPR35 (0.56) GPR35ALDH1A1MAPTMEN1KMT2A
SCHEMBL4800113 0.82 GPR35 (0.59) GPR35PDPK1CYTH3AKT1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4600 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3723864-B1 THICKENED ONE-COMPONENT HAIR TONER HENKEL AG & CO KGAA (DE) 2026-01-14 EP claimed
US-12364660-B2 Granulated hair dye composition WELLA GERMANY GMBH (DE) 2025-07-22 US claimed
WO-2025061335-A1 METHOD FOR DYEING KERATIN FIBRES, COMPRISING THE APPLICATION OF AN OXIDATIVE PRE-TREATMENT AGENT AND A DYE COMPRISING DIRECT DYES HENKEL AG & CO. KGAA (DE) 2025-03-27 WO claimed
US-20240350386-A1 Hair Coloring Compositions Comprising Hydroxyalkyl Amines As Alkalising Agents WELLA GERMANY GMBH (DE) 2024-10-24 US claimed
EP-4247323-B1 GRANULATED HAIR DYE COMPOSITION WELLA GERMANY GMBH (DE) 2024-09-04 EP claimed
US-20230414484-A1 GRANULATED HAIR DYE COMPOSITION WELLA GERMANY GMBH (DE) 2023-12-28 US claimed
CN-117222397-A Granular hair dyeing composition 威娜德国有限责任公司 2023-12-12 CN claimed
EP-4247323-A2 GRANULATED HAIR DYE COMPOSITION Wella Germany GmbH (DE) 2023-09-27 EP claimed
WO-2023017035-A1 HAIR COLORING COMPOSITIONS COMPRISING HYDROXYALKYL AMINES AS ALKALISING AGENTS WELLA GERMANY GMBH (DE) 2023-02-16 WO claimed
EP-4076353-A1 TINTING CONDITIONER HAVING IMPROVED DYEING PERFORMANCE Henkel AG & Co. KGaA (DE) 2022-10-26 EP claimed
EP-0659399-B1 Process of direct hair using steam OREAL (FR) 1997-03-19 EP claimed
EP-0706787-A1 Oxidation hair dye Wella Aktiengesellschaft (DE) 1996-04-17 EP claimed
US-5496377-A HAIR DYES, NITRO-AMINE COMPOUNDS L'OREAL (FR) 1996-03-05 US claimed
EP-0659399-A1 Process of direct hair using steam L'OREAL (FR) 1995-06-28 EP claimed
EP-0376047-B1 2-Amino-6-chloro-4-nitrophenol derivatives, process for their preparation and hair dyeing agent containing the same WELLA AG (DE) 1994-05-04 EP claimed
EP-0480829-B1 Hair dyeing composition containing anthraquinones OREAL (FR) 1994-04-06 EP claimed
US-5226924-A 1,4-DI(MONO- OR POLY) HYDROXYALKYLAMINO-9,10-ANTHRAQUINONES FOR DYEING HUMAN KERATINOUS FIBRES, COSMETIC COMPOSITION CONTAINING THEM IN COMBINATION WITH AZO AND NITROBENZENE DYES, AND HAIR-DYEING PROCESS USING THEM L'OREAL (FR) 1993-07-13 US claimed
EP-0480829-A1 Hair dyeing composition containing anthraquinones L'OREAL (FR) 1992-04-15 EP claimed
WO-1990007557-A1 2-AMINO-6-CHLOR-4-NITROPHENOL DERIVATIVES, PROCESS FOR OBTAINING THEM AND HAIR DYE CONTAINING THESE COMPOUNDS WELLA AKTIENGESELLSCHAFT (DE) 1990-07-12 WO claimed
EP-0376047-A1 2-Amino-6-chloro-4-nitrophenol derivatives, process for their preparation and hair dyeing agent containing the same Wella Aktiengesellschaft (DE) 1990-07-04 EP claimed