Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 11/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 11/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 11/20 | 0.46 |
| ▸ | PIK3R1 | P27986 | 9/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29804264 | 1.00 | PIK3CD (0.46) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R1 | |
| SCHEMBL24682672 | 0.83 | MAPT (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R1 | |
| SCHEMBL29804278 | 0.83 | MAPT (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R1 | |
| SCHEMBL29109955 | 0.82 | PIK3CD (0.46) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R1 | |
| SCHEMBL29804274 | 0.81 | PIK3CD (0.45) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R1 | |
| SCHEMBL24682671 | 0.81 | PIK3CD (0.45) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R1 | |
| SCHEMBL24684276 | 0.77 | MALT1 (0.40) | USP2MAPTSMN1; SMN2AR | |
| SCHEMBL29804167 | 0.77 | MALT1 (0.40) | USP2MAPTSMN1; SMN2AR | |
| SCHEMBL24684252 | 0.77 | AR (0.44) | USP2MAPTSMN1; SMN2ARSCN8A | |
| SCHEMBL24682665 | 0.74 | KMT2A (0.43) | SMN1; SMN2ARSCN8ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117062607-A | Methyl substituted pyridine and pyridazine compounds, derivatives thereof and methods of use thereof | 拉堤果生物医疗股份有限公司 | 2023-11-14 | — | — | CN | disclosed |
| WO-2022192487-A2 | METHYL-SUBSTITUTED PYRIDINE AND PYRIDAZINE COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | LATIGO BIOTHERAPEUTICS, INC. (US) | 2022-09-15 | — | — | WO | disclosed |