Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24682671 | 1.00 | PIK3CD (0.45) | PIK3CDPIK3R1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL29109955 | 0.94 | PIK3CD (0.46) | PIK3CDPIK3R1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL29804278 | 0.87 | MAPT (0.43) | PIK3CDPIK3R1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL24682672 | 0.87 | MAPT (0.43) | PIK3CDPIK3R1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL29804499 | 0.82 | ALDH1A1 (0.43) | ALDH1A1ATMLMNASCN10ASCN8A | |
| SCHEMBL24684261 | 0.82 | ALDH1A1 (0.43) | ALDH1A1ATMLMNASCN10ASCN8A | |
| SCHEMBL24682627 | 0.82 | ALDH1A1 (0.49) | ALDH1A1ATMLMNASCN10ASCN8A | |
| SCHEMBL29804425 | 0.82 | ALDH1A1 (0.49) | ALDH1A1ATMLMNASCN10ASCN8A | |
| SCHEMBL24684271 | 0.81 | PIK3CD (0.46) | PIK3CDPIK3R1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL29804264 | 0.81 | PIK3CD (0.46) | PIK3CDPIK3R1PIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4304585-A2 | METHYL-SUBSTITUTED PYRIDINE AND PYRIDAZINE COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | Latigo Biotherapeutics, Inc. (US) | 2024-01-17 | — | — | EP | disclosed |
| WO-2022192487-A2 | METHYL-SUBSTITUTED PYRIDINE AND PYRIDAZINE COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | LATIGO BIOTHERAPEUTICS, INC. (US) | 2022-09-15 | — | — | WO | disclosed |