Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21912193 | 0.85 | ACE2 (0.41) | EPHX1 | |
| SCHEMBL21291218 | 0.82 | EPHX1 (0.44) | EPHX1 | |
| SCHEMBL23696755 | 0.76 | EPHX1 (0.47) | EPHX1 | |
| SCHEMBL22504912 | 0.76 | TSHR (0.35) | TSHR | |
| SCHEMBL28418574 | 0.75 | TSHR (0.42) | TSHRHRH4HRH3 | |
| SCHEMBL25973013 | 0.74 | EPHX1 (0.50) | TSHREPHX1 | |
| SCHEMBL25110744 | 0.74 | EPHX1 (0.50) | TSHREPHX1 | |
| SCHEMBL19792078 | 0.74 | KMT2A (0.42) | TSHR | |
| SCHEMBL24169976 | 0.74 | FAAH (0.33) | — | |
| SCHEMBL18882750 | 0.74 | TSHR (0.41) | TSHRHRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1939204-B3 | FUSED HETEROCYCLIC DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND MEDICINAL USE THEREOF | KISSEI PHARMACEUTICAL (JP) | 2022-08-24 | — | — | EP | disclosed |