Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 15/20 | 0.68 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2466196 | 0.95 | SCD (0.75) | SCDDCTPP1CYP2C9CYP2C19HTR2B | |
| SCHEMBL2721222 | 0.94 | SCD (0.60) | SCDDCTPP1CYP2C9CYP2C19 | |
| SCHEMBL2720925 | 0.94 | SCD (0.60) | SCDDCTPP1 | |
| SCHEMBL2467222 | 0.91 | SCD (0.64) | SCDDCTPP1CYP2C9CYP2C19HTR2B | |
| SCHEMBL2466218 | 0.90 | SCD (0.70) | SCDDCTPP1 | |
| SCHEMBL2720243 | 0.89 | SCD (0.67) | SCDDCTPP1CYP2C9CYP2C19 | |
| SCHEMBL2721299 | 0.89 | SCD (0.67) | SCDDCTPP1 | |
| SCHEMBL2469792 | 0.89 | SCD (0.63) | SCDDCTPP1 | |
| SCHEMBL2469589 | 0.89 | SCD (0.72) | SCDDCTPP1 | |
| SCHEMBL2721368 | 0.87 | SCD (0.55) | SCDDCTPP1CYP2C9CYP2C19HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651605-B1 | PYRIDYL DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC (CA) | 2012-05-02 | — | — | EP | claimed |
| EP-1846035-B1 | COMBINATION THERAPY | XENON PHARMACEUTICALS INC (CA) | 2011-09-21 | — | — | EP | claimed |