Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 13/20 | 0.67 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2721222 | 0.95 | SCD (0.60) | SCDDCTPP1CYP3A4GAAMAPT | |
| SCHEMBL2466196 | 0.94 | SCD (0.75) | SCDDCTPP1CYP2C9CYP2C19 | |
| SCHEMBL2721299 | 0.93 | SCD (0.67) | SCDDCTPP1SMN1; SMN2 | |
| SCHEMBL2466062 | 0.92 | SCD (0.58) | SCDDCTPP1CYP3A4GAAMAPT | |
| SCHEMBL2468596 | 0.89 | SCD (0.68) | SCDDCTPP1CYP2C9CYP2C19 | |
| SCHEMBL2720925 | 0.89 | SCD (0.60) | SCDDCTPP1SMN1; SMN2 | |
| SCHEMBL1601062 | 0.86 | SCD (0.88) | SCDDCTPP1 | |
| SCHEMBL2466218 | 0.86 | SCD (0.70) | SCDDCTPP1 | |
| SCHEMBL2469413 | 0.86 | SCD (0.74) | SCDDCTPP1 | |
| SCHEMBL2469589 | 0.85 | SCD (0.72) | SCDDCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651605-B1 | PYRIDYL DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC (CA) | 2012-05-02 | — | — | EP | claimed |