Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29793354 | 1.00 | KMT2A (0.56) | KMT2AMAOBMAOASMN1; SMN2HTR1A | |
| SCHEMBL31154557 | 0.95 | KMT2A (0.58) | KMT2AMAOBMAOASMN1; SMN2HTR1A | |
| SCHEMBL29793481 | 0.87 | MAPT (0.46) | KMT2AMAOBMAOASMN1; SMN2RAB9A | |
| SCHEMBL25412442 | 0.87 | KMT2A (0.44) | KMT2AMAOBMAOASMN1; SMN2ESR1 | |
| SCHEMBL29793393 | 0.83 | ESR1 (0.42) | KMT2AMAOBMAOASMN1; SMN2HTR1A | |
| SCHEMBL24686372 | 0.83 | LMNA (0.42) | KMT2AMAOBMAOAHTR1AESR1 | |
| SCHEMBL29793383 | 0.82 | LMNA (0.43) | KMT2AMAOBMAOASMN1; SMN2HTR1A | |
| SCHEMBL29793432 | 0.82 | ESR1 (0.50) | KMT2AMAOBMAOASMN1; SMN2ESR1 | |
| SCHEMBL25412467 | 0.81 | TSHR (0.47) | KMT2ASMN1; SMN2HTR1ARAB9ALMNA | |
| SCHEMBL25412469 | 0.81 | TSHR (0.47) | KMT2ASMN1; SMN2HTR1ARAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760743-B2 | Acyloxy substituted phenyl dithiane derivatives | Renovel Innovations, Inc. | 2023-09-19 | — | — | US | disclosed |
| US-11760743-B2 | Acyloxy substituted phenyl dithiane derivatives | Renovel Innovations, Inc. | 2023-09-19 | — | — | US | disclosed |
| US-20220235024-A1 | ACYLOXY SUBSTITUTED PHENYL DITHIANE DERIVATIVES | Renovel Innovations, Inc. | 2022-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11760743-B2 | Acyloxy substituted phenyl dithiane derivatives | AADAC, TBXA2R, DECR2 | KMT2A 2472/4885MAOB 1311/4885MAOA 1732/4885 |
| US-20220235024-A1 | ACYLOXY SUBSTITUTED PHENYL DITHIANE DERIVATIVES | AADAC, TBXA2R, DECR2 | KMT2A 2472/4885MAOB 1311/4885MAOA 1732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.