Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.97 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | RAB9A | P51151 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | MC4R | P32245 | 1/20 | 0.71 |
| ▸ | SCN4A | P35499 | 1/20 | 0.71 |
| ▸ | MC3R | P41968 | 1/20 | 0.71 |
| ▸ | HTR3A | P46098 | 1/20 | 0.71 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.71 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.71 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 3/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimecaine SCHEMBL1651359 | 0.98 | HPGD (1.00) | HPGDTSHRRAB9AALDH1A1MAPT | |
| Trimecaine SCHEMBL28896832 | 0.98 | HPGD (0.94) | HPGDTSHRRAB9AALDH1A1MAPT | |
| Trimecaine SCHEMBL28896992 | 0.97 | HPGD (0.97) | HPGDTSHRRAB9AALDH1A1MAPT | |
| Trimecaine SCHEMBL28896917 | 0.97 | HPGD (0.97) | HPGDTSHRRAB9AALDH1A1MAPT | |
| Trimecaine SCHEMBL28896834 | 0.97 | HPGD (0.97) | HPGDTSHRRAB9AALDH1A1MAPT | |
| SCHEMBL21261833 | 0.88 | HPGD (0.77) | HPGDTSHRRAB9AALDH1A1MAPT | |
| SCHEMBL2615417 | 0.87 | HPGD (0.74) | HPGDTSHRRAB9AALDH1A1MAPT | |
| SCHEMBL2615419 | 0.87 | HPGD (0.74) | HPGDTSHRRAB9AALDH1A1MAPT | |
| SCHEMBL11654851 | 0.87 | HPGD (0.74) | HPGDTSHRRAB9AALDH1A1MAPT | |
| SCHEMBL10640761 | 0.85 | HPGD (0.71) | HPGDTSHRRAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4876 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260144801-A1 | COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MUSCLE CONDITIONS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2026-05-28 | — | — | US | claimed |
| US-20260137637-A1 | ANESTHETIC AGENT MICRO AND NANO PARTICLES, AND METHODS OF MAKING AND USING THE SAME | HAAS ERIC (US) | 2026-05-21 | — | — | US | claimed |
| US-12622873-B2 | Composition of matter comprising liposomes embedded in a polymeric matrix and methods of using same | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2026-05-12 | — | — | US | claimed |
| EP-4735042-A1 | MERCERIZED DECELLULARIZED PARTICLES FOR SLOW RELEASE APPLICATIONS AND METHODS THEREOF | Spiderwort Biotechnologies Inc. (CA) | 2026-05-06 | — | — | EP | claimed |
| US-20260115156-A1 | INJECTABLE COMPOSITION INCLUDING HYDROGEL CONTAINING ANESTHETIC AGENT | UNIV KOREA RES & BUS FOUND (KR) | 2026-04-30 | — | — | US | claimed |
| US-20260083666-A1 | METHOD OF TREATING DISEASE | CREWS THOMAS M (US) | 2026-03-26 | — | — | US | claimed |
| EP-4436552-B1 | GASTRO-RETENTIVE ORAL DOSAGE UNIT CONTAINING A LOCAL ANAESTHETIC | OREXA B V (NL) | 2026-02-04 | — | — | EP | claimed |
| US-12527756-B2 | Anesthetic agent micro and nano particles, and methods of making and using the same | HAAS ERIC (US) | 2026-01-20 | — | — | US | claimed |
| WO-2025235864-A1 | COATED NEEDLE ADMINISTRATION SYSTEMS | EVOLUS, INC. (US) | 2025-11-13 | — | — | WO | claimed |
| US-20250319025-A9 | COMPOSITIONS COMPRISING MODIFIED PHOSPHOLIPIDS AND USES THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-10-16 | — | — | US | claimed |
| WO-1999055287-A1 | TOPICAL ANESTHETIC FORMULATION | CASTILLO JAMES (US) | 1999-11-04 | — | — | WO | claimed |
| US-5972326-A | Controlled release of pharmaceuticals in the anterior chamber of the eye | IOLTECH (FR) | 1999-10-26 | — | — | US | claimed |
| WO-1999022703-A1 | IMPROVED PERSONAL CARE FORMULATIONS | LURIDENT LTD. (IL) | 1999-05-14 | — | — | WO | claimed |
| WO-1998041171-A1 | CONTROLLED RELEASE OF PHARMACEUTICALS IN THE ANTERIOR CHAMBER OF THE EYE | GALIN MILES A (US) | 1998-09-24 | — | — | WO | claimed |
| US-5785976-A | Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof | PHARMACIA & UPJOHN AB (SE) | 1998-07-28 | — | — | US | claimed |
| US-5635540-A | STABLE MIXTURE OF ETHYLENE OXIDE-PROPYLENE OXIDE COPOLYMER AND WATER AS CARRIER FOR ANTIBIOTICS, FUNGICIDES OR ANESTHETICS, FOR TREATING SKIN DISEASES, BURNS, WOUNDS | THE UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 1997-06-03 | — | — | US | claimed |
| EP-0687172-A1 | SOLID LIPID PARTICLES, PARTICLES OF BIOACTIVE AGENTS AND METHODS FOR THE MANUFACTURE AND USE THEREOF | Pharmacia & Upjohn Aktiebolag (SE) | 1995-12-20 | — | — | EP | claimed |
| WO-1994020072-A1 | SOLID LIPID PARTICLES, PARTICLES OF BIOACTIVE AGENTS AND METHODS FOR THE MANUFACTURE AND USE THEREOF | PHARMACIA AB (SE) | 1994-09-15 | — | — | WO | claimed |
| EP-0002426-B1 | ANTIPERSPIRANT | Playtex-Wallco Aktiebolag (SE) | 1981-10-07 | — | — | EP | claimed |
| EP-0002426-A1 | Antiperspirant | Playtex-Wallco Aktiebolag (SE) | 1979-06-13 | — | — | EP | claimed |