Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | MC4R | P32245 | 1/20 | 0.67 |
| ▸ | SCN4A | P35499 | 1/20 | 0.67 |
| ▸ | MC3R | P41968 | 1/20 | 0.67 |
| ▸ | HTR3A | P46098 | 1/20 | 0.67 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.67 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.67 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2615419 | 1.00 | HPGD (0.74) | HPGDTSHRRAB9AALDH1A1MAPT | |
| SCHEMBL21264137 | 0.91 | HPGD (0.62) | HPGDTSHRRAB9AALDH1A1MAPT | |
| Trimecaine SCHEMBL24692 | 0.87 | HPGD (0.97) | HPGDTSHRRAB9AALDH1A1MAPT | |
| Trimecaine SCHEMBL1651359 | 0.85 | HPGD (1.00) | HPGDTSHRRAB9AALDH1A1MAPT | |
| SCHEMBL21261833 | 0.85 | HPGD (0.77) | HPGDTSHRRAB9AALDH1A1MAPT | |
| Trimecaine SCHEMBL28896832 | 0.85 | HPGD (0.94) | HPGDTSHRRAB9AALDH1A1MAPT | |
| Trimecaine SCHEMBL28896992 | 0.84 | HPGD (0.97) | HPGDTSHRRAB9AALDH1A1MAPT | |
| Trimecaine SCHEMBL28896917 | 0.84 | HPGD (0.97) | HPGDTSHRRAB9AALDH1A1MAPT | |
| Trimecaine SCHEMBL28896834 | 0.84 | HPGD (0.97) | HPGDTSHRRAB9AALDH1A1MAPT | |
| SCHEMBL11654851 | 0.84 | HPGD (0.74) | HPGDTSHRRAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095217-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095217-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | FLI1, CDC73, FOS | HPGD 3517/4885TSHR 784/4885RAB9A 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.