Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | TACR1 | P25103 | 5/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.30 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24693055 | 0.94 | SLC6A2 (0.34) | HCRTR1HCRTR2TACR1PTGDR2 | |
| SCHEMBL24693053 | 0.94 | SLC6A2 (0.34) | HCRTR1HCRTR2TACR1PTGDR2 | |
| SCHEMBL24693333 | 0.94 | SLC6A2 (0.34) | HCRTR1HCRTR2TACR1PTGDR2 | |
| SCHEMBL24694378 | 0.92 | BRD3 (0.33) | TACR1 | |
| SCHEMBL24694371 | 0.92 | BRD3 (0.33) | TACR1 | |
| SCHEMBL24693052 | 0.92 | SLC6A4 (0.33) | HCRTR1HCRTR2TACR1PTGDR2 | |
| SCHEMBL24693320 | 0.92 | MEN1 (0.31) | — | |
| SCHEMBL24693058 | 0.91 | SLC6A2 (0.33) | HCRTR1HCRTR2MAPK8 | |
| SCHEMBL24694373 | 0.91 | HCRTR1 (0.31) | HCRTR1HCRTR2 | |
| SCHEMBL25936124 | 0.91 | HCRTR1 (0.31) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250096-A1 | SUBSTITUTED PHENYL-1H-PYRROLO[2,3-c] PYRIDINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2023-08-10 | — | — | US | disclosed |
| US-20230250096-A1 | SUBSTITUTED PHENYL-1H-PYRROLO[2,3-c] PYRIDINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2023-08-10 | — | — | US | disclosed |
| WO-2022253167-A1 | SUBSTITUTED PHENYL-1H-PYRROLO [2, 3-c] PYRIDINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2022-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250096-A1 | SUBSTITUTED PHENYL-1H-PYRROLO[2,3-c] PYRIDINE DERIVATIVES | MLLT1, BMI1, MEN1 | HCRTR1 4866/4885HCRTR2 4845/4885TACR1 4825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.