Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 11/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24693055 | 1.00 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3TACR1KDM1A | |
| SCHEMBL24693053 | 1.00 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3TACR1KDM1A | |
| SCHEMBL24694378 | 0.95 | BRD3 (0.33) | SLC6A2SLC6A4SLC6A3TACR1 | |
| SCHEMBL24694371 | 0.95 | BRD3 (0.33) | SLC6A2SLC6A4SLC6A3TACR1 | |
| SCHEMBL24693052 | 0.95 | SLC6A4 (0.33) | SLC6A2SLC6A4SLC6A3TACR1HCRTR1 | |
| SCHEMBL24693302 | 0.94 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3TACR1KDM1A | |
| SCHEMBL24693295 | 0.94 | HCRTR1 (0.32) | TACR1HCRTR1HCRTR2PTGDR2 | |
| SCHEMBL24693322 | 0.94 | SLC6A2 (0.31) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24694041 | 0.93 | TLR9 (0.33) | SLC6A2SLC6A4SLC6A3TACR1 | |
| SCHEMBL24693298 | 0.92 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3KDM1APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253167-A1 | SUBSTITUTED PHENYL-1H-PYRROLO [2, 3-c] PYRIDINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2022-12-08 | — | — | WO | disclosed |