Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGF2 | P09038 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | M6PR | P20645 | 2/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | IDUA | P35475 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.38 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL850007 | 0.98 | FGF2 (0.45) | FGF2AKT1M6PRSUCNR1IDUA | |
| SCHEMBL18030805 | 0.98 | FGF2 (0.45) | FGF2AKT1M6PRSUCNR1IDUA | |
| SCHEMBL21586585 | 0.98 | FGF2 (0.45) | FGF2AKT1M6PRSUCNR1IDUA | |
| SCHEMBL24212702 | 0.98 | FGF2 (0.45) | FGF2AKT1M6PRSUCNR1IDUA | |
| SCHEMBL18067350 | 0.98 | FGF2 (0.45) | FGF2AKT1M6PRSUCNR1IDUA | |
| SCHEMBL7152405 | 0.98 | FGF2 (0.45) | FGF2AKT1M6PRSUCNR1IDUA | |
| SCHEMBL13478949 | 0.98 | FGF2 (0.45) | FGF2AKT1M6PRSUCNR1IDUA | |
| SCHEMBL23343942 | 0.98 | FGF2 (0.45) | FGF2AKT1M6PRSUCNR1IDUA | |
| SCHEMBL21134565 | 0.98 | FGF2 (0.45) | FGF2AKT1M6PRSUCNR1IDUA | |
| SCHEMBL13523545 | 0.98 | FGF2 (0.45) | FGF2AKT1M6PRSUCNR1IDUA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234287-A1 | IMIDAZOPYRIDAZINE DERIVATIVES USEFUL AS TRK INHIBITORS | BENEVOLENTAI BIO LIMITED (GB) | 2022-11-10 | — | — | WO | disclosed |