SCHEMBL850007

SCHEMBL850007

COC1OC(C(=O)O)C(O)C(O)C1O

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ FGF2 P09038 1/20 0.45
▸ M6PR P20645 2/20 0.44
▸ AKT1 P31749 1/20 0.43
▸ IDUA P35475 1/20 0.43
▸ KDM4E B2RXH2 2/20 0.41
▸ ALDH1A1 P00352 2/20 0.41
▸ HPGD P15428 2/20 0.41
▸ GLA P06280 1/20 0.41
▸ MAPK1 P28482 1/20 0.41
▸ HSD17B10 Q99714 1/20 0.41
▸ HPSE Q9Y251 2/20 0.39
▸ SUCNR1 Q9BXA5 1/20 0.39
▸ G6PD P11413 1/20 0.37
▸ LGALS8 O00214 1/20 0.37
▸ CYP2C8 P10632 1/20 0.36
▸ KDM1A O60341 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18067350 1.00 FGF2 (0.45) FGF2M6PRAKT1IDUAKDM4E
SCHEMBL18030805 1.00 FGF2 (0.45) FGF2M6PRAKT1IDUAKDM4E
SCHEMBL13523545 1.00 FGF2 (0.45) FGF2M6PRAKT1IDUAKDM4E
SCHEMBL24212702 1.00 FGF2 (0.45) FGF2M6PRAKT1IDUAKDM4E
SCHEMBL7152405 1.00 FGF2 (0.45) FGF2M6PRAKT1IDUAKDM4E
SCHEMBL23343942 1.00 FGF2 (0.45) FGF2M6PRAKT1IDUAKDM4E
SCHEMBL13478949 1.00 FGF2 (0.45) FGF2M6PRAKT1IDUAKDM4E
SCHEMBL21134565 1.00 FGF2 (0.45) FGF2M6PRAKT1IDUAKDM4E
SCHEMBL21586585 1.00 FGF2 (0.45) FGF2M6PRAKT1IDUAKDM4E
SCHEMBL14208597 1.00 FGF2 (0.45) FGF2M6PRAKT1IDUAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024137619-A1 ANTI-CLAUDIN, BIS-BENZIMID AZOLE STING AGONIST IMMUNOCONJUGATES, AND USES THEREOF BOLT BIOTHERAPEUTICS, INC. (US) 2024-06-27 — — WO disclosed
WO-2024129956-A1 THIENOAZEPINE IMMUNOCONJUGATES, AND USES THEREOF BOLT BIOTHERAPEUTICS, INC. (US) 2024-06-20 — — WO disclosed
WO-2024110905-A1 ANTI-CEA ANTIBODY DRUG CONJUGATES AND METHODS OF USE BEIGENE, LTD. (KY) 2024-05-30 — — WO disclosed
WO-2024086744-A2 COMPOSITIONS AND USES THEREOF SOLVE THERAPEUTICS, INC. (US) 2024-04-25 — — WO disclosed
US-20230293716-A1 ELASTASE-SUBSTRATE, PEPTIDE LINKER IMMUNOCONJUGATES, AND USES THEREOF BOLT BIOTHERAPEUTICS, INC. (US) 2023-09-21 — — US disclosed
US-20230293716-A1 ELASTASE-SUBSTRATE, PEPTIDE LINKER IMMUNOCONJUGATES, AND USES THEREOF BOLT BIOTHERAPEUTICS, INC. (US) 2023-09-21 — — US disclosed
WO-2023076599-A1 TLR AGONIST IMMUNOCONJUGATES WITH CYSTEINE-MUTANT ANTIBODIES, AND USES THEREOF BOLT BIOTHERAPEUTICS, INC. (US) 2023-05-04 — — WO disclosed
WO-2023275715-A1 METABOLITES OF SELECTIVE ANDROGEN RECEPTOR MODULATORS PFIZER INC. (US) 2023-01-05 — — WO disclosed
WO-2022234287-A1 IMIDAZOPYRIDAZINE DERIVATIVES USEFUL AS TRK INHIBITORS BENEVOLENTAI BIO LIMITED (GB) 2022-11-10 — — WO disclosed
WO-2022204536-A1 2-AMINO-4-CARBOXAMIDE-BENZAZEPINE IMMUNOCONJUGATES, AND USES THEREOF BOLT BIOTHERAPEUTICS, INC. (US) 2022-09-29 — — WO disclosed
WO-2008052086-A1 BENZODIOXANE DERIVATIVES AND USES THEREOF WYETH (US) 2008-05-02 — — WO disclosed
WO-2008052087-A1 CHROMANE DERIVATIVES AND USES THEREOF WYETH (US) 2008-05-02 — — WO disclosed
WO-2007141513-A1 USE OF COUMARIN DERIVATIVES IN ANTIFUNGAL THERAPY NOVABIOTICS LIMITED (GB) 2007-12-13 — — WO disclosed
US-20070275936-A1 Formulations and Treatment Methods BIOVIE INC. 2007-11-29 — — US disclosed
US-20070275936-A1 Formulations and Treatment Methods BIOVIE INC. 2007-11-29 — — US disclosed
US-20070129282-A1 Pharmaceutical treatments and compositions BIOVIE INC. 2007-06-07 — — US disclosed
US-20070129282-A1 Pharmaceutical treatments and compositions BIOVIE INC. 2007-06-07 — — US disclosed
WO-2007005568-A1 A-[(E)-2-(5,6,7,8-TETRAHYDRO-5,5,8,8-TETRAMETHYL-2-NAPTHALENYL)-1-PROPENYL]BENZOIC ACID ANALOGS AND METHOD OF MANUFACTURE AND AND USE THEREOF WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2007-01-11 — — WO disclosed
US-20060241176-A1 Dihydrobenzofuran derivatives and uses thereof WYETH (US) 2006-10-26 — — US disclosed
US-20060241176-A1 Dihydrobenzofuran derivatives and uses thereof WYETH (US) 2006-10-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070129282-A1 Pharmaceutical treatments and compositions HSD3B1, HSD3B2, HSD17B1 FGF2 2402/4885M6PR 4739/4885AKT1 2629/4885
US-20230293716-A1 ELASTASE-SUBSTRATE, PEPTIDE LINKER IMMUNOCONJUGATES, AND USES THEREOF SERPINB1, ELANE, CELA1 FGF2 2794/4885M6PR 1639/4885AKT1 4243/4885
US-20060241176-A1 Dihydrobenzofuran derivatives and uses thereof HTR1F, HTR2C, HTR1A FGF2 1202/4885M6PR 1246/4885AKT1 1861/4885
US-20070275936-A1 Formulations and Treatment Methods HSD3B1, HSD17B1, HSD17B3 FGF2 2262/4885M6PR 4669/4885AKT1 2507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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