Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 20/20 | 0.45 |
| ▸ | OGFRL1 | Q5TC84 | 14/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 9/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2437467 | 0.86 | OPRM1 (0.59) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| Isocitrate SCHEMBL2469617 | 0.83 | OPRM1 (0.47) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL2467942 | 0.78 | OPRM1 (0.59) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL12792041 | 0.77 | OPRM1 (0.62) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL6527673 | 0.77 | OPRM1 (0.55) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL2437531 | 0.77 | OPRM1 (0.57) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL2439790 | 0.76 | OPRM1 (0.60) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL2469666 | 0.75 | OPRM1 (0.53) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL2434544 | 0.75 | OPRM1 (0.61) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL2436209 | 0.74 | OPRM1 (0.49) | OPRM1OGFRL1OPRL1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2260042-B1 | SUBSTITUTED SPIROCYCLIC CYCLOHEXANE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2011-09-21 | — | — | EP | disclosed |