Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24696001 | 0.92 | KDM4E (0.38) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL24696386 | 0.91 | KDM4E (0.38) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL24696342 | 0.91 | KDM4E (0.38) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL24695812 | 0.91 | KDM4E (0.38) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL24695643 | 0.90 | SMN1; SMN2 (0.39) | KDM4EALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL24695973 | 0.90 | SMN1; SMN2 (0.39) | KDM4EALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL24695605 | 0.90 | KDM4E (0.41) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL24695845 | 0.88 | KDM4E (0.38) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL24695846 | 0.87 | KDM4E (0.36) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL24696246 | 0.87 | KDM4E (0.40) | KDM4EALDH1A1HPGDPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255408-A1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-12-08 | — | — | WO | disclosed |