Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 4/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | FABP2 | P12104 | 1/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | GUSB | P08236 | 1/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22221466 | 0.91 | PPARA (0.58) | KMT2AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL24696699 | 0.89 | SMN1; SMN2 (0.56) | KMT2AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL22221457 | 0.86 | PPARA (0.56) | KMT2AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL22221494 | 0.86 | SMN1; SMN2 (0.53) | KMT2AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL22221753 | 0.86 | SMN1; SMN2 (0.53) | KMT2AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL24696889 | 0.86 | MEN1 (0.52) | KMT2AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL22221754 | 0.85 | SMN1; SMN2 (0.53) | KMT2AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL22221501 | 0.85 | PPARA (0.59) | KMT2AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL22221759 | 0.84 | MAPT (0.54) | KMT2AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL24697351 | 0.83 | LMNA (0.53) | KMT2AMAPTSMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220304957-A1 | ANTI-CANCER COMPOSITIONS AND METHODS OF USE | UNIV LOUISIANA STATE (US) | 2022-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220304957-A1 | ANTI-CANCER COMPOSITIONS AND METHODS OF USE | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, TP53, MCL1 | KMT2A 2060/4885MAPT 3049/4885SMN1; SMN2 3030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.