⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24071799 | 1.00 | — | — | |
| SCHEMBL18722790 | 1.00 | — | — | |
| SCHEMBL24697016 | 1.00 | — | — | |
| SCHEMBL24827893 | 0.89 | — | — | |
| SCHEMBL22779666 | 0.88 | TRPA1 (0.34) | — | |
| SCHEMBL14508370 | 0.86 | — | — | |
| SCHEMBL21776141 | 0.86 | — | — | |
| SCHEMBL12885833 | 0.86 | — | — | |
| SCHEMBL10188197 | 0.86 | — | — | |
| SCHEMBL24828023 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253250-A1 | BRUTON'S TYROSINE KINASE DEGRADER CONTAINING FUSED-RING OR SPIRO-RING | 正大天晴药业集团股份有限公司 | 2022-12-08 | — | — | WO | disclosed |