Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KHK | P50053 | 4/20 | 0.37 |
| ▸ | RXRA | P19793 | 3/20 | 0.35 |
| ▸ | RXRB | P28702 | 3/20 | 0.35 |
| ▸ | RXRG | P48443 | 3/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30016653 | 1.00 | MEN1 (0.38) | MEN1KMT2AKHKRXRARXRB | |
| SCHEMBL30015509 | 1.00 | MEN1 (0.38) | MEN1KMT2AKHKRXRARXRB | |
| SCHEMBL30015676 | 1.00 | MEN1 (0.38) | MEN1KMT2AKHKRXRARXRB | |
| SCHEMBL30016121 | 0.92 | ALDH1A1 (0.40) | MEN1KMT2AKHKALDH1A1PDK1 | |
| SCHEMBL24699135 | 0.92 | ALDH1A1 (0.40) | MEN1KMT2AKHKALDH1A1PDK1 | |
| SCHEMBL30016169 | 0.89 | MEN1 (0.35) | MEN1KMT2AKHKALDH1A1PDE10A | |
| SCHEMBL30015516 | 0.89 | MEN1 (0.35) | MEN1KMT2AKHKALDH1A1PDE10A | |
| SCHEMBL24699526 | 0.88 | MEN1 (0.40) | MEN1KMT2AKHKALDH1A1PDE10A | |
| SCHEMBL24698854 | 0.88 | MEN1 (0.40) | MEN1KMT2AKHKALDH1A1PDE10A | |
| SCHEMBL24699528 | 0.88 | MEN1 (0.40) | MEN1KMT2AKHKALDH1A1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |